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Emphysema
Lung disease caused by smoking

by Jerry Kennard
for About.com

Updated July 22, 2006

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

carson.jpg

Emphysema sufferer Johnny Carson

image:www.museum.tv

Popular talk-show host Johnny Carson has died of emphysema (January 2005). Emphysema is one of a group of diseases called COPD, chronic obstructive pulmonary disease that causes progressive damage to the lungs.

Bare facts about emphysema

  • Of 16 million Americans with COPD, 2 million have emphysema.

  • Each year over 120,000 Americans die of emphysema according to the American Lung Association.
  • COPD is the fourth largest cause of mortality in the U.S.

  • At the present time more men than women aged between 50 and 70 years have emphysema. This pattern is changing as more women take up smoking.

    What is emphysema
    Emphysema is a progressive disease of the airways that is characterized by a gradual loss of lung function. This serious lung disease causes damage that cannot be cured or reversed although there are treatments that can lead to some improvement in lung function. Emphysema is a result of the toxin destroying the small air sacs in the lungs, called alveoli. The air sacs stretch as they transport oxygen from the air to the blood and then shrink as they force out carbon dioxide. The lungs lose their elasticity as a result. Exhaling becomes difficult and air becomes trapped in the lungs trap air and cannot effectively exchange it with fresh air. The damaged lungs are not able to provide the body with the oxygen it needs. The result is that people's lives are transformed. In severe cases any form of physical exertion causes breathing to become so labored that quality of life is minimal. The inability to breath freely is emotionally exhausting and very frightening.

    Causes of emphysema
    Cigarette smoking is the major cause of emphysema. It accounts for more than 80 percent of all cases. Most victims are over 40 years of age and have been long term smokers.
    Exposure to the toxins in air pollution is also thought to be contributing factor of emphysema.
    There is a rare inherited form of emphysema called alpha-1 antitrypsin. People with this deficiency are more likely than others to get emphysema.

    Signs and Symptoms of smphysema

  • Shortness of breath (dyspnea)

  • Wheezing, coughing

  • A feeling of tightness in the chest

  • People with emphysema develop a barrel-like distended chest

  • Chronic fatigue

  • Weight loss

  • Difficulty sleeping

  • Morning headaches

  • Swelling of the ankles

  • Produce sputum or phlegm when coughing
  • Treatments for emphysema
    The most important treatment is prevention by not smoking. Thereafter treatment options that your doctor may advise include;
    Antibiotics:
    Broad-spectrum antibiotics, such as ampicillin, may help combat respiratory infections and help prevent further damage to the lungs.
    Anti-inflammatory medications (corticosteroids):
    Steroids such as prednisolone may be used to minimize inflammation associated with emphysema.
    Bronchodilators:
    These medications help open up constricted airways and make breathing easier.
    Oxygen therapy:
    Supplemental oxygen can benefit the patient whose lung function is severely impaired.
    Exercise programs:
    Exercise programs can help improve independence and quality of life. It cannot make any significant improvement to the damaged lungs affected by emphysema.
    Lung reduction surgery:
    In this procedure small portions of the lung are cut to allow healthy tissue room to expand. This increases the amount of oxygen to the body and helps relieve breathing problems.
    Lung transplantation:
    Where all other treatment options have failed lung transplantation may be an option. It is risky, expensive and will only be appropriate for a small number of people.
    Prolastin:
    is an FDA approved treatment for A1AD-related emphysema. The replacement therapy of Prolastin raises the level of AAT in the blood and may protect the lung tissue from the destructive enzyme.

    Prevention of emphysema
    Stop smoking before damage is evident. Preventive measures such as flu shots, the pneumonia vaccine, prompt treatment of respiratory infection and a good balanced diet can make a positive contribution to prevent further lung damage.

    Article Sources: American Lung Association, CDC Centers for Disease Control, National Emphysema Foundation, National Institutes for Health, National Lung Health Education Program

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